90 Results for "

Piper betle L.

" in MedChemExpress (MCE) Product Catalog:
Products (90)

90 Results for "Piper betle L." in MCE Product Catalog:

3
Aurantiamide acetate
Aurantiamide acetate
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3 Cited Publications
Art. -Nr.: HY-N2905
CAS. Nr.: 56121-42-7
Synonyms: Asperglaucide
Category:  

Natural Products Portulacaceae Plants Portulaca oleracea Linn. Disease Research Fields Inflammation/Immunology

Target:  

Cathepsin

Aurantiamide acetate (TMC-58A) is a selective and orally active cathepsin inhibitor isolated from Portulaca oleracea L. Aurantiamide acetate has anti-inflammatory activities and can be used for the study of inflammatory diseases .
2
Kavain
Kavain
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2 Cited Publications
Art. -Nr.: HY-N2096
CAS. Nr.: 3155-48-4
Category:  

Natural Products Piperaceae Piper methysticum G.Forst. Plants

Target:  

GABA Receptor

Kavain is a class of kavalactone isolated from Piper methysticum, which has anxiolytic properties in animals and humans. Kavain positively modulated γ-Aminobutyric acid type A (GABAA) receptor .
1
4-Allylcatechol
4-Allylcatechol
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1 Cited Publications
Art. -Nr.: HY-N1887
CAS. Nr.: 1126-61-0
Synonyms: Hydroxychavicol; 4-Allylpyrocatechol
Category:  

Ophiopogon japonicus (L. f.) Ker-Gawl. Liliaceae Other Diseases Phenols Polyphenols Plants Disease Research Fields

Target:  

Bacterial Antibiotic TNF Receptor Interleukin Related

4-Allylcatechol (4-Allylpyrocatechol) is a xylan which has oral activity and can be isolated from the root of Piper taiwanense. 4-Allylcatechol has a strong inhibitory activity against collagen-induced platelet aggregation (IC50 = 5.3 μM). In addition, 4-Allylcatechol has anti-tuberculosis activity against Mycobacterium tuberculosis H37Rv (MIC = 27.6 μg/mL) .
1
Piperlonguminine
Piperlonguminine
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1 Cited Publications
Art. -Nr.: HY-126562
CAS. Nr.: 5950-12-9
Reinheit:  99.31%
Category:  

Cardiovascular Disease Infection Alkaloids Capsicum annuum L. Neurological Disease Plants Solanaceae Disease Research Fields Inflammation/Immunology

Target:  

Bacterial Fungal Antibiotic

Piperlonguminine is an alkaloid amide isolated from the Piper species. Piperlonguminine shows various biological properties, including anti-inflammatory, antitumor, neuroprotective, anti-platelet, anti-melanogenic, antifungal and antibacterial activities .
Dihydromethysticin
Dihydromethysticin
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Art. -Nr.: HY-N0921
CAS. Nr.: 19902-91-1
Synonyms: (+)-Dihydromethysticin
Category:  

Natural Products other families Plants Disease Research Fields Inflammation/Immunology

Target:  

Carboxylesterase (CES) NOD-like Receptor (NLR) Apoptosis

Dihydromethysticin is an orally active natural active ingredient. Dihydromethysticin can be extracted from Piper methysticum. Dihydromethysticin inhibits carboxylesterase 1 (Ki = 68.2 μM) and CYP2A5. Dihydromethysticin upregulates NLRC3 and induces Apoptosis. Dihydromethysticin exhibits anticancer activity against colorectal cancer and lung adenoma .
Pellitorine
Pellitorine
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Art. -Nr.: HY-N3097
CAS. Nr.: 18836-52-7
Category:  

Alkaloids Other Alkaloids Piperaceae Plants Disease Research Fields Piper nigrum Linn. Biological Pesticide Research Cancer Agricultural Research

Target:  

TRP Channel Amyloid-β Toll-like Receptor (TLR) Keap1-Nrf2 Heme Oxygenase (HO) Dihydroorotate Dehydrogenase Ferroptosis PAI-1 NF-κB ERK Proton Pump Glutathione Peroxidase Thrombin Insecticide Bacterial

Pellitorine is a bioactive natural amide compound. Pellitorine can competitively antagonize the activation of TRPV1 by Capsaicin (HY-10448), thereby reducing pain signal transmission. Pellitorine improves cognitive dysfunction by upregulating the BDNF-ERK1/2-CREB and Nrf2-HO-1 pathways. Pellitorine exerts anti-inflammatory and anti-sepsis effects by inhibiting the release of high mobility group protein B1 (HMGB1) and the expression of RAGE/TLR4. Pellitorine exerts its antithrombotic effect by prolonging the clotting time, inhibiting the activity of clotting factors and thrombin. Pellitorine inhibits lipid peroxidation and resists ferroptosis by upregulating GPX4 and DHODH. Pellitorine kills Aedes aegypti mosquito larvae by inhibiting V-type H⁺-ATPase and aquaporin 4 (AaAQP4). Pellitorine exhibits anti-cancer activity (e.g., leukemia and breast cancer) and has inhibitory effects on certain bacteria .
(+)-Kavain
(+)-Kavain
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Art. -Nr.: HY-B1671
CAS. Nr.: 500-64-1
Category:  

Piperaceae Piper methysticum G.Forst. Other Phenylpropanoids Phenylpropanoids Plants

Target:  

GABA Receptor Sodium Channel Calcium Channel

(+)-Kavain, a main kavalactone that can be extracted from Piper methysticum, has anticonvulsive properties, attenuating vascular smooth muscle contraction through interactions with voltage-dependent Na + and Ca 2+ channels . (+)-Kavain is shown to bind at the α4β2δ GABAA receptor and potentiate GABA efficacy . (+)-Kavain is used as a treatment for inflammatory diseases, its anti-inflammatory action has been widely studied .
Desmethoxyyangonin
Desmethoxyyangonin
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Art. -Nr.: HY-N0918
CAS. Nr.: 15345-89-8
Synonyms: Demethoxyyangonin; 5,6-Dehydrokavain
Category:  

other families Other Diseases Other Phenylpropanoids Phenylpropanoids Plants Disease Research Fields

Target:  

Monoamine Oxidase JAK IKK STAT NO Synthase Cytochrome P450

Desmethoxyyangonin is one of the six major kavalactones found in the Piper methysticum (kava) plant. Desmethoxyyangonin is a selective inhibitor of monoamine oxidase-B (MAO-B) (IC50: 0.123  µM). Desmethoxyyangonin exerts anti-inflammatory effects by inhibiting Jak2/STAT3 and IKK signaling pathways. Desmethoxyyangonin induces CYP3A23 expression and leads to skeletal muscle relaxation .
Kadsurenone
Kadsurenone
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Art. -Nr.: HY-N10663
CAS. Nr.: 95851-37-9
Category:  

Hernandia sonora Linn. other families Lignans Piperaceae Phenylpropanoids Plants Piper kadsura (Choisy) Ohwi

Target:  

Platelet-activating Factor Receptor (PAFR)

Kadsurenone is a lignan with specific antagonistic activity against platelet-activating factor. Kadsurenone can be derived from the stem of Piper kadsura .
Tridecane
Tridecane
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Art. -Nr.: HY-W088037
CAS. Nr.: 629-50-5
Category:  

Natural Products Piper aduncum L. Other Diseases Piperaceae Plants Disease Research Fields

Target:  

Environmental Pollutants

Tridecane is a short chain aliphatic hydrocarbon containing 13 carbon atoms. Tridecane is an volatile oil component isolated from essential oil of Piper aduncum L. Tridecane is a stress compound released by the brown marmorated stink bugs stress compound .
β-Phenylethyl β-D-glucoside
β-Phenylethyl β-D-glucoside
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Art. -Nr.: HY-W357140
CAS. Nr.: 18997-54-1
Synonyms: Phenylethyl β-D-glucopyranoside
Category:  

Piperaceae Piper crocatum Ruiz & Pav. Plants Saccharides Monosaccharides

Target:  

Fungal

β-Phenylethyl β-D-glucoside (Phenylethyl β-D-glucopyranoside) (Compound 7), a phenolic compounds, is an antifungal agent. β-Phenylethyl β-D-glucoside can be isolated from the leaves of Piper crocatum. β-Phenylethyl β-D-glucoside has antifungal activity against Candida albicans. β-Phenylethyl β-D-glucoside can be used for fungal infections research .
Methylsticin
Methylsticin
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Art. -Nr.: HY-N2465
CAS. Nr.: 495-85-2
Category:  

Piperaceae Piper methysticum G.Forst. Other Phenylpropanoids Phenylpropanoids Plants Disease Research Fields Inflammation/Immunology

Target:  

Others

Methylsticin is a kavalactone isolated from the Piper methysticum . Methylsticin exhibit osteoclast formation inhibitory activity .
Tridecane-d28
Tridecane-d28
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Art. -Nr.: HY-W088037S
CAS. Nr.: 121578-12-9
Tridecane-d28 is the deuterium labeled Tridecane . Tridecane is a short chain aliphatic hydrocarbon containing 13 carbon atoms. Tridecane is an volatile oil component isolated from essential oil of Piper aduncum L. Tridecane is a stress compound released by the brown marmorated stink bugs stress compound .
Piperic acid
Piperic acid
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Art. -Nr.: HY-121909
CAS. Nr.: 136-72-1
Target:  

Bacterial

Forschungsgebiete:  

Infection

Piperic acid is a natural antioxidant and antibacterial agent. Piperic acid can be used in food preservation and human health .
3-(3,4,5-Trimethoxyphenyl)propanoic acid
3-(3,4,5-Trimethoxyphenyl)propanoic acid
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Art. -Nr.: HY-W022390
CAS. Nr.: 25173-72-2
Category:  

Ketones, Aldehydes, Acids Other Diseases Endogenous metabolite Disease Research Fields

Target:  

Endogenous Metabolite

3-(3,4,5-Trimethoxyphenyl)propanoic acid is found in herbs and spices. 3-(3,4,5-Trimethoxyphenyl)propanoic acid is a constituent of Piper longum (long pepper) and Piper retrofractum (Javanese long pepper).
Futoquinol
Futoquinol
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Art. -Nr.: HY-N3915
CAS. Nr.: 28178-92-9
Category:  

Piperaceae Other Phenylpropanoids Phenylpropanoids Plants Piper kadsura (Choisy) Ohwi

Target:  

NO Synthase

Futoquinol is a neolignan isolated from the dried aerial parts of Piper kadsura (Piperaceae). Futoquinol potently inhibits NO production in microglia cells. Futoquinol has anti-neuroinflammatory activities .
Pipercide
Pipercide
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Art. -Nr.: HY-N10743
CAS. Nr.: 54794-74-0
Category:  

Natural Products Piperaceae Plants Piper nigrum Linn.

Target:  

Parasite

Pipercide is an amide of piper nigrum fruits. Pipercide has larvicidal activity to mosquito. Pipercide acts on the nervous system and induces repetitive discharge on the central nerve cord. Pipercide can be used as an insecticide .
Hancinone C
Hancinone C
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Art. -Nr.: HY-N3987
CAS. Nr.: 111843-10-8
Category:  

Lignans Piperaceae Piper hancei Maxim. Phenylpropanoids Plants

Target:  

Others

Hancinone C (compound 2) is a natural product that can be found in Piper hancei .
Isochavicine
Isochavicine
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Art. -Nr.: HY-N0144B
CAS. Nr.: 30511-77-4
Category:  

Alkaloids Piperidine Alkaloids Piperaceae Plants Piper retrofractum Vahl

Target:  

Others

Isochavicine is an alkaloids that can be isolated from Piper retrofractum. Isochavicine inhibits the seedling growth of cress with I50 values of 11 μM .
Black pepper oleoresin
Black pepper oleoresin
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Art. -Nr.: HY-204591
CAS. Nr.: 84929-41-9
Target:  

Drug Derivative

Forschungsgebiete:  

Others

Black pepper oleoresin is a substance extracted from the pepper plant (Piper nigrum), which has aroma, spiciness, and bioactive components. It is widely used in food, health products, cosmetics, and daily chemical products.
Assay Types